everolimus相关论文
Tuberous sclerosis complex (TSC) is a rare multisystem, autosomal dominant neurocutaneous syndrome in which epilepsy is ......
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PU6445 Analysis of clinicopathological features and precision therapy of pseudomyogenic hemangioendo
Objective To investigate the clinicopathological features,misdiagnosis reson and precision therapy to pseudomyogenic hem......
Establishment and characterisation of lfabp-EGFP-LC3 transgenic zebrafish: an in vivo model system t
In recent years, autophagy has emerged as an important theme in biology and medicine, mainly due to its increasingly und......
Objective: The mTOR inhibitors have been demonstrated clinical benefits in many cancers(kidney,breast cancer,etc),while ......
目的评价依维莫司洗脱支架(everolimus eluting stent, Xience V)治疗急性冠脉综合征(acute coronary syndrome,ACS)的临床效果.方......
目的：观察依维莫司治疗晚期非小细胞肺癌（NSCLC）的临床疗效及不良反应。方法选取2013年6月至2014年6月解放军总医院收治的晚期 NSCLC ......
目的评价联用依维莫司治疗乳腺癌的疗效与安全性。方法检索有关数据库，收集在乳腺癌新辅助治疗或辅助治疗中联用依维莫司(试验组)或......
In order to evaluate the effectiveness of everolimus vs.rapamycin in the treatment of diabetic nephropathy,8-week old di......
依维莫司是一种口服的雷帕霉素抑制剂,已经被批准用于多种实体瘤的治疗,但是部分患者在使用依维莫司后出现了高血糖的不良反应.在......
依维莫司(everolimus,Afinitor(R))是目前唯一已上市的口服哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂,在国际上已被批准用于治疗晚期肾......
考察他莫昔芬联合依维莫司对雌激素受体 (Estrogen receptor, ER) 阳性转移性乳腺癌的临床治疗效果.将116例ER阳性转移性乳腺癌患......
,MNK1 inhibitor CGP57380 overcomes mTOR inhibitor-induced activation of eIF4E: the mechanism of syne
Although the treatment of adult T-cell acute lymphoblastic leukemia (T-ALL) has been significantly improved,the heteroge......
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Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genet
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乙二醇依次与叔丁基二苯基氯硅烷、对甲基苯磺酰氯、溴化钠反应生成(2-溴乙氧基)叔丁基二苯基硅烷,再与西罗莫司、三氟甲磺酸银反......
目的 探讨心脏移植术后免疫抑制治疗中依维莫司(EVR)部分或完全替代环孢素A(CsA)的有效性和安全性.方法 在Pubmed等3个数据库中检......
目的：探讨依维莫司治疗晚期乳腺癌所致间质性肺炎的临床特点和治疗策略。方法：分析3例依维莫司联合化疗或内分泌治疗晚期乳腺癌所致......
目的 探讨mTOR抑制剂依维莫司对人脑胶质瘤细胞自噬作用的影响. 方法 体外培养胶质瘤细胞株87-MG、U251、SHG-44,给予不同浓度的......
靶向激素受体（hormone receptor，HR）和人类表皮生长因子（human epidermal growth factor receptor 2，HER-2）对激素受体阳性乳腺癌的治疗......
BACKGROUND The EverProTM(Sahajanand Laser Technology Ltd.,India)everolimus-eluting coronary stent system(EES)is a second......
目的评价肾移植术后钙调蛋白阻滞剂（CNI）撤除后雷帕霉素受体阻滞剂（TOR—I）免疫抑制替代治疗的疗效和安全性。方法检索MEDLINE、EMbase......
目的建立大鼠颈动脉球囊损伤模型,观察依维莫司对大鼠颈动脉球囊损伤后再狭窄的影响。方法 36只雄性SD大鼠随机分为对照组、损伤组......
目的：观察依维莫司对大鼠实验性Ig A肾病的作用并初步探讨其机制。方法：建立实验性Ig A肾病大鼠模型,实验共分为正常对照（control）组、......
靶向激素受体（hormone receptor，HR）和人类表皮生长因子（human epidermal growth factor receptor2，HER-2）对激素受体阳性乳腺癌的治疗至......
目的:回顾性分析我院诊治的结节硬化症合并肾错构瘤患者的临床资料,并结合分析国内外相关文献资料,以期提高对该病的认识及诊治水......
目的探讨比卡鲁胺对雄激素受体(AR)阳性乳腺癌细胞侵袭迁移能力的影响及相关作用机制,以及mTOR抑制剂依维莫司联合比卡鲁胺对MDA-M......
目的探讨雷帕霉素靶蛋白(mTOR)抑制剂依维莫司与全反式维甲酸(ATRA)联用对小细胞肺癌细胞株NCI-H446增殖及迁移能力的影响。方法将......
目的：观察依维莫司对高糖诱导肾小球系膜细胞（HBZY-1）凋亡的保护作用,并探讨其意义。方法：将培养HBZY-1细胞按不同葡萄糖和依维莫司浓......
目的：建立LC-MS/MS法同时测定人全血中环孢素A、依维莫司、他克莫司和西罗莫司的浓度。方法：人全血样品用乙腈沉淀蛋白后,上清液用叔......
目的从作用机制、药代动力学性质及影响因素、临床评价、不良反应等方面简述依维莫司在器官移植领域的临床应用。方法查阅近几年文......
目的评估依维莫司治疗转移性肾癌的疗效和安全性。方法回顾性分析2013年6月至2014年6月应用依维莫司治疗的12例转移性肾癌患者的资......
Amenorrhea as a rare drug-related adverse event associated with everolimus for pancreatic neuroendoc
The patient was an asymptomatic 43-year-old woman. Abdominal ultrasonography and enhanced computed tomography showed a t......
Amenorrhea as a rare drug-related adverse event associated with everolimus for pancreatic neuroendoc
The patient was an asymptomatic 43-year-old woman. Abdominal ultrasonography and enhanced computed tomography showed a t......
AIM: To investigate whether the simultaneous treatment with human growth hormone(h GH) abolishes the negative effects of......
目的：观察哺乳类动物雷帕霉素靶蛋白（mTOR）抑制剂依维莫司对糖尿病肾病的保护作用。方法：12只db/m非糖尿病小鼠和12只db/db糖尿病小鼠......
美国食品药品监督管理局（FDA）于2010年4月20日批准诺华公司的Zortress（通用名：Everolimus，依维莫司）一项新的适应证，该药将可以用于具有轻......
Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genet
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目的通过使用哺乳动物雷帕霉素靶蛋白m TOR抑制药依维莫司抑制A549细胞m TOR信号通路,研究依维莫司是否具有放射增敏作用。方法单......
目的：回顾性分析依维莫司联合内分泌治疗对内分泌治疗耐药型激素受体阳性转移性乳腺癌患者的疗效和安全性。方法自2013年7月至2015......
Successful Tacrolimus Therapy Extended by Everolimus in Retroperitoneal Angiomyolipoma after Lung Tr
Lymphangioleiomyomatosis (LAM) is a rare disease that affects women, especially in child-bearing age. Clinical manifesta......
Combining cytochrome P-450 3A4 modulators and cyclosporine or everolimus in transplantation is succe
AIM:To describe the long term follow-up of kidney allograft recipients receiving ketoconazole with calcineurin inhibitor......
目的比较佐他莫司和依维莫司两类药物洗脱支架的长期临床安全性和有效性。方法纳入2011年1月至2012年12月于武汉亚洲心脏病医院接......
About 75%of all breast cancers are estrogen receptor(ER)-positive.They generally have a more favorable clinical behavior......
Although thymic epithelial tumors(TETs)are rare in the general population,they represent the most frequently diagnosed p......
Neuroendocrine tumors resistant to mammalian target of rapamycin inhibitors:A difficult conversion f
Deregulation of the phosphoinositide 3-kinase(PI3K)/protein kinase B(Akt)-mammalian target of rapamycin(mTOR)signaling p......
虽然医学研究表明，药物洗脱支架与裸金属支架相比，能有效地减少血管再狭窄和再血管化，但是围绕着药物洗脱支架的安全性及有效性一直存......
